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Thread: Interesting results from giving breast cancer patients Tramadol after surgery.

  1. #1
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    Default Interesting results from giving breast cancer patients Tramadol after surgery.

    According to this study, those who were prescribed Tramadol after breast cancer surgery, had a decreased risk of reoccurrence.

    "RESULTS:

    Of 2588 breast cancer patients, 36.4% had received tramadol. Those who received tramadol had a 0.71-fold decreased risk of recurrence and a 0.56-fold decrease in mortality. The MCF-7 cell viability assays showed that tramadol had an anti-proliferative effect by cell cycle arrest, suppressing colony formation, and regulation of oestrogen and progesterone receptors. Tramadol induced apoptosis of MCF-7 cells via extracellular signal-regulated kinases by decreasing of 5-hydroxytryptamine (HT)2B receptor and transient receptor potential vanilloid-1 expression.

    CONCLUSIONS:

    After breast cancer surgery, patients who received tramadol had a decreased risk of postoperative recurrence and mortality. The anti-tumour effect of tramadol appears to involve inhibition of proliferation, induction of apoptosis, and effects on 5-HT2B receptor and TRPV-1."

    Here is a link to the study: https://www.ncbi.nlm.nih.gov/pubmed/31591020
    Last edited by Artknowsme; 12-04-2019 at 03:04 PM.
    Counting on someone else for your happiness is a recipe for premeditated disappointment.

  2. #2
    @Artknowsme thank you.

    Forwarded the link to a friend of mine who had been diagnosed with breast cancer several years ago. She's OK now, though.

  3. #3
    Quote Originally Posted by Artknowsme View Post
    According to this study, those who were prescribed Tramadol after breast cancer surgery, had a decreased risk of reoccurrence.

    "RESULTS:

    Of 2588 breast cancer patients, 36.4% had received tramadol. Those who received tramadol had a 0.71-fold decreased risk of recurrence and a 0.56-fold decrease in mortality. The MCF-7 cell viability assays showed that tramadol had an anti-proliferative effect by cell cycle arrest, suppressing colony formation, and regulation of oestrogen and progesterone receptors. Tramadol induced apoptosis of MCF-7 cells via extracellular signal-regulated kinases by decreasing of 5-hydroxytryptamine (HT)2B receptor and transient receptor potential vanilloid-1 expression.

    CONCLUSIONS:

    After breast cancer surgery, patients who received tramadol had a decreased risk of postoperative recurrence and mortality. The anti-tumour effect of tramadol appears to involve inhibition of proliferation, induction of apoptosis, and effects on 5-HT2B receptor and TRPV-1."

    Here is a link to the study: https://www.ncbi.nlm.nih.gov/pubmed/31591020
    Wow! I don't even know what else to say- just wow and thank you, Art!
    Likes windowpane, Artknowsme, ludwig1961 liked this post
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