Interesting results from giving breast cancer patients Tramadol after surgery.

Artknowsme

Honorable member
Posts
283
According to this study, those who were prescribed Tramadol after breast cancer surgery, had a decreased risk of reoccurrence.

"RESULTS:

Of 2588 breast cancer patients, 36.4% had received tramadol. Those who received tramadol had a 0.71-fold decreased risk of recurrence and a 0.56-fold decrease in mortality. The MCF-7 cell viability assays showed that tramadol had an anti-proliferative effect by cell cycle arrest, suppressing colony formation, and regulation of oestrogen and progesterone receptors. Tramadol induced apoptosis of MCF-7 cells via extracellular signal-regulated kinases by decreasing of 5-hydroxytryptamine (HT)2B receptor and transient receptor potential vanilloid-1 expression.

CONCLUSIONS:

After breast cancer surgery, patients who received tramadol had a decreased risk of postoperative recurrence and mortality. The anti-tumour effect of tramadol appears to involve inhibition of proliferation, induction of apoptosis, and effects on 5-HT2B receptor and TRPV-1."

Here is a link to the study: https://www.ncbi.nlm.nih.gov/pubmed/31591020
 
Last edited:

Mrs Parker

Exalted member
Posts
4,099
According to this study, those who were prescribed Tramadol after breast cancer surgery, had a decreased risk of reoccurrence.

"RESULTS:

Of 2588 breast cancer patients, 36.4% had received tramadol. Those who received tramadol had a 0.71-fold decreased risk of recurrence and a 0.56-fold decrease in mortality. The MCF-7 cell viability assays showed that tramadol had an anti-proliferative effect by cell cycle arrest, suppressing colony formation, and regulation of oestrogen and progesterone receptors. Tramadol induced apoptosis of MCF-7 cells via extracellular signal-regulated kinases by decreasing of 5-hydroxytryptamine (HT)2B receptor and transient receptor potential vanilloid-1 expression.

CONCLUSIONS:

After breast cancer surgery, patients who received tramadol had a decreased risk of postoperative recurrence and mortality. The anti-tumour effect of tramadol appears to involve inhibition of proliferation, induction of apoptosis, and effects on 5-HT2B receptor and TRPV-1."

Here is a link to the study: https://www.ncbi.nlm.nih.gov/pubmed/31591020
Wow! I don't even know what else to say- just wow and thank you, Art!
 
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