- Jun 28, 2011
Depending on why you get the migraines, acetaminophen + diphenhydramine might help. The ratio for me is 1000mg Tylenol + 25mg of benedryl. I prefer a product that contained an antihistamine called phenyltoloxamine. The OTC version is no longer available though. I think it is available by prescription as Z-gesic or Flextra-650. I plan on asking my provider next time I see her.