Amoxicillin And Clavulanate Potassium

 
4.5 (3)
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More about Amoxicillin And Clavulanate Potassium

What is/are Amoxicillin And Clavulanate Potassium?

Amoxicillin/clavulanic acid (INN) or co-amoxiclav (BAN) is a combination antibiotic consisting of amoxicillin trihydrate, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. This combination results in an antibiotic with an increased spectrum of action and restored efficacy against amoxicillin-resistant bacteria that produce β-lactamase.

Unlike co-trimoxazole, the BAN has not been widely adopted internationally. Trade names include Augmentin (by GlaxoSmithKline), Clavamox (by Pfizer), and many others.

Medical uses

Amoxicillin/clavulanic acid is widely used to treat many infections caused by susceptible bacteria, such as urinary tract infections, respiratory tract infections, skin and soft tissue infections, and infections caused by the bacterial flora of the mouth, such as dental infections, infected animal bites, and infected human bites (including uncomplicated "clenched-fist" or "reverse-bite" injuries).

Adverse effects

Possible side effects include diarrhea, vomiting, nausea, thrush, and a skin rash. These do not usually require medical attention. As with all antimicrobial agents, antibiotic-associated diarrhea due to Clostridium difficile ("C. diff'") infection—sometimes leading to pseudomembranous colitis—may occur during or after treatment with amoxicillin/clavulanic acid.

Rarely, cholestatic jaundice (also referred to as cholestatic hepatitis, a form of liver toxicity) has been associated with amoxicillin/clavulanic acid. The reaction may occur up to several weeks after treatment has stopped, and usually takes weeks to resolve. It is more frequent in men, older people, and those who have taken long courses of treatment; the estimated overall incidence is 1 in 100,000 exposures. In the United Kingdom, co-amoxiclav carries a warning from the Committee on Safety of Medicines to this effect.

As all aminopenicillins, amoxicillin has been associated with Stevens–Johnson syndrome/toxic epidermal necrolysis, although these reactions are very rare.

This article uses material from the Wikipedia article Amoxicillin And Clavulanate Potassium, which is released under the Creative Commons Attribution-Share-Alike License 3.0.

Reviews for Amoxicillin And Clavulanate Potassium

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3 reviews

Overall rating
 
4.5
Overall satisfaction
 
4.5(3)
Efficacy
 
4.7(3)
Lack of side effects
 
4.2(3)
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Overall rating
 
4.8
Overall satisfaction
 
4.5
Efficacy
 
5.0
Lack of side effects
 
5.0
Very effective

Worked great only had diarrhea on the second day but otherwise very effective.

Relevant Brand Name and Medical Condition

Brand Name
Augmentin
Medical Condition
Bacteremia

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How long have you taken this medicine for?
0-1 months
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Overall rating
 
4.0
Overall satisfaction
 
4.0
Efficacy
 
4.0
Lack of side effects
 
4.0
Worked best for this type of infection

No stomach upset, slight constipation. Worked best for this type of infection.

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Brand Name
Augmentin
Medical Condition
Urinary Tract Infection

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How long have you taken this medicine for?
1 month - 6 months
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Overall rating
 
4.5
Overall satisfaction
 
5.0
Efficacy
 
5.0
Lack of side effects
 
3.5
Worked great for me

My preferred broad spectrum anti-biotic. I have been prescribed this twice over the years for severe bronchitis. Worked much better than amoxicillian alone (or anything else) that I have been prescribed that for the same thing over the years (what seems to be every other year bronchitis). Side effects (stomach, intestines---gues it is killing all the good bacteria too) moderate the first few days but then they went away for me. Pretty typical side effect with any anti-biotic for me anyway, just a little more severe with Augmentin. Big pill (850mg total active ingredients I think).

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Brand Name
Augmentin
Medical Condition
Bacteremia

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How long have you taken this medicine for?
0-1 months
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4 reviews
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