Ethambutol

 
0.0 (0)
This page displays reviews written by users of all forms of Ethambutol. You can also choose to see reviews only for a specific medical condition or brand name.
Medical Conditions

More about Ethambutol

What is/are Ethambutol?

Ethambutol (commonly abbreviated EMB or simply E) is a bacteriostatic antimycobacterial drug prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis drugs, such as isoniazid, rifampicin and pyrazinamide.

It is sold under the trade names Myambutol and Servambutol.

Adverse effects

  • Optic neuritis (hence contraindicated in children below six years of age)
  • Red-green colour blindness
  • Peripheral neuropathy
  • Arthralgia
  • Hyperuricaemia
  • Vertical nystagmus
  • Milk skin reaction

Mechanism of action

Ethambutol is bacteriostatic against actively growing TB bacilli. It works by obstructing the formation of cell wall. Mycolic acids attach to the 5'-hydroxyl groups of D-arabinose residues of arabinogalactan and form mycolyl-arabinogalactan-peptidoglycan complex in the cell wall. It disrupts arabinogalactan synthesis by inhibiting the enzyme arabinosyl transferase. Disruption of the arabinogalactan synthesis inhibits the formation of this complex and leads to increased permeability of the cell wall.

Pharmacokinetics

It is well absorbed from the gastrointestinal tract and well distributed in body tissues and fluids. 50% is excreted unchanged in urine.

This article uses material from the Wikipedia article Ethambutol, which is released under the Creative Commons Attribution-Share-Alike License 3.0.


Medicine Photos

Hover or click on a photo to enlarge it.

Medicine containing Myambutol

Medicine containing Ethambutol

This page uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the page and product and does not endorse or recommend this or any other product.

Reviews for Ethambutol

See reviews for a different combination of brand names and medical conditions:
     
There are no user reviews for this listing.
Already have an account?
Ratings
Overall satisfaction
Efficacy
Lack of side effects
Relevant Brand Name and Medical Condition
Additional Information
Please tell us about your experience with this medicine