Ethinyl Estradiol and Etonogestrel

 
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More about Ethinyl Estradiol and Etonogestrel

What is/are Ethinyl Estradiol and Etonogestrel?

Ethinyl estradiol (EE) /ˌɛθɨnɨlˌiːstrəˈdaɪ.əl/, also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl œstradiol, is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.

Transdermal ethinyl estradiol carries a greater risk of clot formation and venous thromboembolism than 17 beta estradiol, which some have theorized to be related to different amounts of hepatic metabolism after absorption. The same contraindications and precautions apply for EE as with other estrogen medications.

Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism. EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.

The major concern with unopposed estrogen is of endometrial cancer. As such, the medication is generally prescribed with progesterone in the setting of birth control.

Adverse effects

  •     Sudden numbness or weakness, especially on one side of the body;
  •     Sudden and severe headache, confusion, problems with vision, speech, or balance;
  •     Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  •     Sudden cough, wheezing, rapid breathing, coughing up blood;
  •     Pain, swelling, warmth, or redness in one or both legs;
  •     A change in the pattern or severity of migraine headaches;
  •     Nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  •     Sswelling in your hands, ankles, or feet;
  •     A breast lump; or
  •     Symptoms of depression (sleep problems, weakness, tired feeling, mood changes).

Less serious side effects of ethinyl estradiol / etonogestrel may include:

  •     Mild nausea, vomiting, bloating, stomach cramps, changes in weight or appetite;
  •     Breast pain, tenderness, or swelling;
  •     Headache, nervousness, dizziness, tired feeling;
  •     Freckles or darkening of facial skin, increased hair growth, loss of scalp hair;
  •     Problems with contact lenses; or
  •     Vaginal itching or discharge, changes in your menstrual periods, decreased sex drive.

This article uses material from the Wikipedia article Ethinyl Estradiol and Etonogestrel, which is released under the Creative Commons Attribution-Share-Alike License 3.0.

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