Hydroxyzine

 
4.2 (1)
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More about Hydroxyzine

What is/are Hydroxyzine?

Hydroxyzine (/haɪˈdrɒksɨziːn/; sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine classes. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year,[2] and is still in widespread use today.

Due to its antagonistic effects on several receptor systems in the brain, hydroxyzine is claimed to have strong anxiolytic and mild antiobsessive as well as antipsychotic properties.[3] Today it is used primarily for the symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Because of its antihistamine effects it can also be used for the treatment of severe cases of itching, hyperalgesia and motion sickness-induced nausea.[4][5] Even though it is an effective sedative, hypnotic, analgesic, and tranquilizer, it allegedly shares virtually none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons.

Hydroxyzine has been used in medical practice with opioid analgesics to increase the analgesic efficacy of opioids, and by recreational drug users to maximise the effects of opiates, and/or preempt some side effects of opioids like itching, nausea, and vomiting.

Common uses

This medicine is an antihistamine used to treat anxiety, to relieve itching caused by allergic conditions, and to cause drowsiness. It may also be used to treat other conditions as determined by your doctor.

Before using

Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.

Directions

Follow the directions for using this medicine provided by your doctor. This medicine may be taken with food if it upsets your stomach. Store this medicine at room temperature in a tightly-closed container, away from heat and light. If you miss a dose of this medicine and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions

This medicine will add to the effects of other depressants and alcohol. Ask your pharmacist if you have questions about which medicines are depressants. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. Caution should be used in the elderly since they may be more sensitive to the effects of this drug.

For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if this drug is excreted in breast milk. Do not breast-feed while taking this medicine.

Possible side effects

Side effects, that may go away during treatment, include drowsiness or dry mouth. If they continue or are bothersome, check with your doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual drowsiness and dizziness.

Additional information

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.

Drug interactions

Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

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Medicine containing Hydroxyzine

This page uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the page and product and does not endorse or recommend this or any other product.

Reviews for Hydroxyzine

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1 reviews

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4.2
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4.5  (1)
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5.0  (1)
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shayna is a member of the Pharmacy Reviewer forum
Total Posts: 4164
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Very helpful for hives and anxiety and more

I have had this medicine used on me over the years for a variety of uses, from migraine/nausea to hives and for general anxiety. I find it to be one of the most versatile drugs on hand.

I sometimes will take this along with a Klonopin for faster relief since the Klonopin takes a couple of hours to really kick in.

The only downside is marked drowsiness -- which sometimes can be a most welcome side effect. This is also a strong antihistamine so one may get dry mouth and the typical dried out nose feeling as well. This is easily relieved by drinking more water and using saline nose drops.

Relevant Brand Name and Medical Condition

Brand Name
Atarax
Medical Condition
Anxiety

Additional Information

How long have you taken this medicine for?
More than 2 years
S
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