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More about Latanoprost

What is/are Latanoprost?

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension by reducing intraocular pressure. It is a prostaglandin analogue (more specifically an analogue of prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes (through the uvealsclearal tract).

It is also known by the brand name of Xalatan manufactured by Pfizer. Annual sales are approximately $1.6 billion. The patent for latanoprost expired in March 2011, and at least one generic version (manufactured by Mylan Inc.) is now widely available in the U.S. The Veterans Health Administration, part of the U.S. Department of Veterans Affairs, uses generic lantanoprost manufactured by Alcon Laboratories distributed by Falcon Pharmaceuticals, both of Fort Worth Texas. Latanoprost was developed by Carl B. Camras and his research adviser László Z. Bitó at Columbia University in 1996.

Adverse effects

Possible side effects:

  •     May eventually cause permanent darkening of the iris to brown (heterochromia);
  •     May cause reddening of the eyes (hyperemia)
  •     May cause blurred vision;
  •     May cause eyelid redness;
  •     May permanently darken eyelashes;
  •     May cause eye discomfort;
  •     May cause a temporary burning sensation during use.
  •     May cause thickening of the eyelashes.
  •     Rarely, herpes simplex keratitis.
  •     A single case report links latanoprost use to the progression of keratoconus.

This article uses material from the Wikipedia article Latanoprost, which is released under the Creative Commons Attribution-Share-Alike License 3.0.

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