Aldoril (Methyldopa)

 
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Aldoril is one brand name of the medicine also known by its generic name Methyldopa. This page displays only reviews left by users of Aldoril. Click here to see all reviews left for all forms of Methyldopa. You can also choose other review combinations.
Medical Conditions

More about Methyldopa

What is/are Methyldopa?

Methyldopa (L-α-Methyl-3,4-dihydroxyphenylalanine; Aldomet, Aldoril, Dopamet, Dopegyt, etc.) is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (also known as pregnancy-induced hypertension (PIH)).

Adverse effects

Methyldopa is capable of inducing a number of adverse side effects, which range from mild to severe. Nevertheless, they are generally mild when the dose is less than 1 gram per day. Side effects may include:

    Psychological

  •         Depression and/or even suicidal ideation, as well as nightmares
  •         Apathy and/or anhedonia, as well as dysphoria
  •         Anxiety, especially of the social anxiety variant
  •         Decreased alertness, awareness, and wakefulness
  •         Impaired attention, focus, and concentration
  •         Decreased desire, drive, and motivation
  •         Fatigue or lethargy and/or malaise or lassitude
  •         Sedation or drowsiness and/or somnolence or sleepiness
  •         Agitation or restlessness
  •         Cognitive and memory impairment
  •         Derealization and/or depersonalization, as well as mild psychosis
  •         Sexual dysfunction including impaired libido, desire, and drive

    Physiological

  •         Dizziness, lightheadedness, or vertigo
  •         Miosis or pupil constriction
  •         Xerostomia or dry mouth
  •         Gastrointestinal disturbances such as diarrhea and/or constipation
  •         Headache or migraine
  •         Myalgia or muscle aches, arthralgia or joint pain, and/or paresthesia ("pins and needles")
  •         Restless legs syndrome (RLS)
  •         Parkinsonian symptoms such as muscle tremors, rigidity, hypokinesia, and/or balance or postural instability
  •         Akathisia, ataxia, dyskinesia as well as even tardive dyskinesia, and/or dystonia
  •         Bell's palsy or facial paralysis
  •         Sexual dysfunction consisting of impaired erectile dysfunction and/or anorgasmia
  •         Hyperprolactinemia or excess prolactin, gynecomastia/breast enlargement in males, and/or amenorrhoea or absence of menstrual cycles in females
  •         Bradycardia or decreased heart rate
  •         Hypotension or decreased blood pressure (though this may also be considered a therapeutic benefit)
  •         Orthostatic hypotension (also known as postural hypotension)
  •         Hepatitis, hepatotoxicity, or liver dysfunction or damage
  •         Pancreatitis or inflammation of the pancreas
  •         Haemolytic anaemia or deficiency in red blood cells (RBCs)
  •         Myelotoxicity or bone marrow suppression, potentially leading to thrombocytopenia or blood platelet deficiency and/or leukopenia or white blood cell (WBC) deficiency
  •         Hypersensitivity such as lupus erythematosus, myocarditis, and/or pericarditis
  •         Lichenoid reactions such as skin lesions and/or rashes
  •         Pallor

This article uses material from the Wikipedia article Methyldopa, which is released under the Creative Commons Attribution-Share-Alike License 3.0.

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Medicine containing Methyldopa

This page uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the page and product and does not endorse or recommend this or any other product.

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