What is/are Valganciclovir?
Valganciclovir hydrochloride (Valcyte, manufactured by Hoffmann–La Roche (Roche), and also known as Cymeval, Valcyt, Valixa, Darilin, Rovalcyte, Patheon, and Syntex) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
It has been proposed that valganciclovir could be used in the treatment of chronic fatigue syndrome. Following some reported success in 9 out of 12 patients at Stanford University in California, a follow-up double-blind, controlled study of 30 patients was completed, and although data has not yet been released, according to the Virus Induced CNS Dysfunction Association, "the data Dr. Montoya presented at the 2008 International Conference on HHV-6&7 indicated that patients on Valcyte experienced significant cognitive improvement.", especially for those with elevated antibody levels to HHV-6 and EBV (VCA and EA)
- Blood: neutropenia, anemia, low platelets. Myelosuppression is one of the main side effects that may limit prolonged use of valganciclovir.
- Gastrointestinal: diarrhea, nausea, vomiting, abdominal pain.
- Central nervous system: fever, headache, insomnia, paresthesia, and peripheral neuropathy.
- Ocular: retinal detachment
This article uses material from the Wikipedia article Valganciclovir, which is released under the Creative Commons Attribution-Share-Alike License 3.0.