What is/are Verteporfin?
Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels. Verteporfin is also used off-label for the treatment of central serous retinopathy.
AMost commonly, blurred vision. Also, photosensitivity; it is advised to avoid exposure to sunlight and unscreened lighting until 48 hours after the injection of verteporfin.
- Severe decrease in vision;
- Sudden and severe pain;
- Severe redness or other discoloration of your eyes;
- Eye pain or seeing halos around lights;
- Feeling like you might pass out;
- Chest pain; or
- Flushing (warmth, redness, or tingly feeling).
Less serious side effects of verteporfin may include:
- Slight changes in your vision, seeing flashes of light;
- Dry eyes;
- Redness, swelling, or itching of your eyelids;
- Feeling weak or tired;
- Mild itching or skin rash;
- Constipation, nausea;
- Joint pain, muscle weakness;
- Fever, chills, body aches, sore throat, flu symptoms; or
- Pain, swelling, bleeding, or itching where the medicine was injected.
This article uses material from the Wikipedia article Verteporfin, which is released under the Creative Commons Attribution-Share-Alike License 3.0.